Truth of One of the most used Medicine ASPIRIN, and why not to use it until prescribed by Registered Medical Practitioner!?

Aspirin, Disprin etc. Are the medicine which were used on a wide scale for the most common reason fever, headache etc.

These medicine contains Aspirin which is Salicylate comes under the category of NSAIDs, the category in which Paracetamol comes.

So what is the difference that b/w Paracetamol and Aspirin, And why to Prefer Paracetamol in spite of Aspirin.

Answer :- COX 2 cycle is responsible for the headache and fever because of Prostaglandin synthesis.

Aspirin blocks the COX 1, COX 2 and as well as TXA (thromboxigenase cycle) and works as Analgesic and Antipyretic.

The disadvantage is it blocks TXA cycle which is responsible for the coagulative property, which helps to stop profuse bleeding. So Aspirin Blocks TXA and causes Bleeding problem.
So in case of Dengue people takes Aspirin for fever which cause Dengue Haemorrhagic syndrome which also may leads to death.

Paracetamol preferentially blocks COX 2 and not to TXA, and hence works specifically for Fever and Headache purposes.

So everyone should prefer PARACETAMOL, not to aspirin !!

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